Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alkaline phosphatase, germ cell type' and Ligand = 'BDBM396270'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alkaline phosphatase, germ cell type (Homo sapiens (Human))	BDBM396270 (US10314827, Compound 13) Show SMILES C[C@@H]1[C@H]2[C@@H](C[C@H](C)CN2CCNCC(=O)c2ccccc2)O[C@]11CC[C@H]2[C@@H]3CC[C@@H]4CC(=O)CC[C@]4(C)[C@H]3CC2=C(C)C1 |r,t:45| Show InChI InChI=1S/C38H54N2O3/c1-24-18-35-36(40(23-24)17-16-39-22-34(42)27-8-6-5-7-9-27)26(3)38(43-35)15-13-30-31-11-10-28-19-29(41)12-14-37(28,4)33(31)20-32(30)25(2)21-38/h5-9,24,26,28,30-31,33,35-36,39H,10-23H2,1-4H3/t24-,26+,28+,30-,31-,33-,35+,36-,37-,38-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<20	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description C3H10T1/2 cells were plated in 96 wells with a density of 8×103 cells/well. Cells were grown to confluence (72 hrs). After sonic Hedgehog (250 ng/ml)...				Bioorg Med Chem Lett 18: 1994-9 (2008) BindingDB Entry DOI: 10.7270/Q2QR50GW
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