Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase' and Ligand = 'BDBM235185'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235185 (US9365558, 8 | US9822074, 8) Show SMILES CCS(=O)(=O)NC(=O)C1=C(C[C@](NC1=O)(c1ccc(OCCCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(OC(F)F)cc1 |r,t:8| Show InChI InChI=1S/C28H28F8N2O6S/c1-2-45(41,42)38-24(40)22-21(17-6-10-20(11-7-17)44-25(29)30)16-26(28(34,35)36,37-23(22)39)18-8-12-19(13-9-18)43-15-5-3-4-14-27(31,32)33/h6-13,25H,2-5,14-16H2,1H3,(H,37,39)(H,38,40)/t26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosphat...				US Patent US9822074 (2017) BindingDB Entry DOI: 10.7270/Q2K939TM
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM235185 (US9365558, 8 | US9822074, 8) Show SMILES CCS(=O)(=O)NC(=O)C1=C(C[C@](NC1=O)(c1ccc(OCCCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(OC(F)F)cc1 |r,t:8| Show InChI InChI=1S/C28H28F8N2O6S/c1-2-45(41,42)38-24(40)22-21(17-6-10-20(11-7-17)44-25(29)30)16-26(28(34,35)36,37-23(22)39)18-8-12-19(13-9-18)43-15-5-3-4-14-27(31,32)33/h6-13,25H,2-5,14-16H2,1H3,(H,37,39)(H,38,40)/t26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	7.4	65
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well Polypropylene plates, in a total volume of 60 μL of 50 mM Potassium Phosph...				US Patent US9365558 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T8B
					More data for this Ligand-Target Pair