Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase' and Ligand = 'BDBM253643'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM253643 (US9701672, 72) Show SMILES COc1ccc(cn1)C1=C(C#N)C(=O)N[C@@](C1)(c1ccc(OCCCCCC(F)(F)F)cc1)C(F)(F)F |r,c:9| Show InChI InChI=1S/C25H23F6N3O3/c1-36-21-10-5-16(15-33-21)19-13-23(25(29,30)31,34-22(35)20(19)14-32)17-6-8-18(9-7-17)37-12-4-2-3-11-24(26,27)28/h5-10,15H,2-4,11-13H2,1H3,(H,34,35)/t23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.3	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				US Patent US9701672 (2017) BindingDB Entry DOI: 10.7270/Q2DV1MXW
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