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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase' and Ligand = 'BDBM50090651'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase


(Homo sapiens (Human))		BDBM50090651
PNG
(CHEMBL3581729)
Show SMILES Fc1ccc(NS(=O)(=O)c2ccc(NC(=O)OCc3ccccc3)c(c2)N2CCCC2=O)c(F)c1
Show InChI InChI=1S/C24H21F2N3O5S/c25-17-8-10-20(19(26)13-17)28-35(32,33)18-9-11-21(22(14-18)29-12-4-7-23(29)30)27-24(31)34-15-16-5-2-1-3-6-16/h1-3,5-6,8-11,13-14,28H,4,7,12,15H2,(H,27,31)
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n/an/a 14n/an/an/an/an/an/a



Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of full length human MGAT2 transfected in FreeStyle293 cells assessed as dioleoylglycerol by RapidFire/MS assay

J Med Chem 58: 3892-909 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00178
BindingDB Entry DOI: 10.7270/Q2XK8H94
More data for this
Ligand-Target Pair