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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor' and Ligand = 'BDBM50019985'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))		BDBM50019985
PNG
(2-{4-[4-(4,4-Dimethyl-2,6-dioxo-piperidin-1-yl)-bu...)
Show SMILES COC(=O)c1cccnc1N1CCN(CCCCN2C(=O)CC(C)(C)CC2=O)CC1
Show InChI InChI=1S/C22H32N4O4/c1-22(2)15-18(27)26(19(28)16-22)10-5-4-9-24-11-13-25(14-12-24)20-17(21(29)30-3)7-6-8-23-20/h6-8H,4-5,9-16H2,1-3H3
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n/an/a 37n/an/an/an/an/an/a



Bristol-Myers Company

Curated by ChEMBL


Assay Description
Ability to inhibit [3H]WB-4101 binding to rat cortical alpha-1-adrenergic receptor

J Med Chem 31: 618-24 (1988)


BindingDB Entry DOI: 10.7270/Q2222SR2
More data for this
Ligand-Target Pair