Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor' and Ligand = 'BDBM50227300'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50227300 (CHEMBL146844) Show SMILES COC(C)COC1CCN(CC1)c1nc(N)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C19H28N4O4/c1-12(24-2)11-27-13-5-7-23(8-6-13)19-21-15-10-17(26-4)16(25-3)9-14(15)18(20)22-19/h9-10,12-13H,5-8,11H2,1-4H3,(H2,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity for alpha-1 adrenergic receptor by displacement of [3H]-prazosin from rat brain homogenate preparation				J Med Chem 31: 516-20 (1988) BindingDB Entry DOI: 10.7270/Q2ZP48BH
					More data for this Ligand-Target Pair