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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor' and Ligand = 'BDBM50280810'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))		BDBM50280810
PNG
(5-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-1-hydrox...)
Show SMILES OC(CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc2NC(=O)Cc2c1
Show InChI InChI=1S/C22H25FN2O2/c23-19-4-1-15(2-5-19)11-16-7-9-25(10-8-16)14-21(26)17-3-6-20-18(12-17)13-22(27)24-20/h1-6,12,16,21,26H,7-11,13-14H2,(H,24,27)
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Similars
Article
n/an/a 183n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for the Alpha-1 adrenergic receptor affinity in a standard radioligand binding assay with [3H]- prazosin

Bioorg Med Chem Lett 3: 91-94 (1993)


Article DOI: 10.1016/S0960-894X(00)80098-0
BindingDB Entry DOI: 10.7270/Q2GT5N4S
More data for this
Ligand-Target Pair