Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50057463 (1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piper...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati S.p.A. Curated by ChEMBL | Assay Description The binding affinity of the compound was determined towards Alpha-1A adrenergic receptor in the COS cell line. | J Med Chem 42: 427-37 (1999) Article DOI: 10.1021/jm9805337 BindingDB Entry DOI: 10.7270/Q2FN15CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Homo sapiens (Human)) | BDBM50057463 (1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piper...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 10.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Recordati S.p.A. Curated by ChEMBL | Assay Description The binding affinity of the compound was determined towards Alpha-1C adrenergic receptor in the COS cell line. | J Med Chem 42: 427-37 (1999) Article DOI: 10.1021/jm9805337 BindingDB Entry DOI: 10.7270/Q2FN15CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (CALF) | BDBM50057463 (1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piper...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Central Research Curated by ChEMBL | Assay Description Binding affinity was tested on cloned bovine Alpha-1A adrenergic receptor | J Med Chem 40: 1293-315 (1997) Article DOI: 10.1021/jm960697s BindingDB Entry DOI: 10.7270/Q2W096MN | |||||||||||
More data for this Ligand-Target Pair |