Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of [3H]p-aminoclonidine (PAC) binding to alpha-2 adrenergic receptor of purified human platelet plasma membranes | J Med Chem 30: 1241-4 (1987) BindingDB Entry DOI: 10.7270/Q2JM2CWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Compound was evaluated for the displacement of [3H]yohimbine in acetonitrile/acetic acid anti-corynanthine MIPs for Alpha-2 adrenergic receptor | Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ05ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | 5.0 | n/a |
TBA | Assay Description Alpha-2 adrenergic receptor binding activity was determined by displacement of [3H]yohimbine in 50 mM phosphate buffer pH 5.0/Tween 20 where the poly... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ05ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank | n/a | n/a | 1.95E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Compound was evaluated for the displacement of [3H]yohimbine in acetonitrile/acetic acid where the polymer is anti-yohimbin MIPs for Alpha-2 adrenerg... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ05ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank | n/a | n/a | 3.98E+5 | n/a | n/a | n/a | n/a | 5.0 | n/a |
TBA | Assay Description Compound was evaluated for the displacement of [3H]yohimbine in 50 mM phosphate buffer pH 5.0/Tween 20 where the polymer is anti-yohimbin MIPs for Al... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ05ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank | n/a | n/a | n/a | 4.70E+4 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dissociation constant in high affinity sites where the binding is in acetonitrile/acetic acid for Alpha-2 adrenergic receptor | Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ05ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank | n/a | n/a | n/a | 4.70E+4 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dissociation constant in high affinity sites where the binding is in acetonitrile/acetic acid for Alpha-2 adrenergic receptor | Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ05ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank | n/a | n/a | n/a | 5.40E+6 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dissociation constant in low affinity sites where the binding is in acetonitrile/acetic acid for Alpha-2 adrenergic receptor | Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ05ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank | n/a | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dissociation constant in high affinity sites where the binding is in 50 mM phosphate buffer for Alpha-2 adrenergic receptor | Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ05ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank | n/a | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dissociation constant in low affinity sites where the binding is in 50 mM phosphate buffer for Alpha-2 adrenergic receptor | Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ05ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank | n/a | n/a | n/a | 5.40E+6 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dissociation constant in low affinity sites where the binding is in acetonitrile/acetic acid for Alpha-2 adrenergic receptor | Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ05ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank | n/a | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dissociation constant in high affinity sites where the binding is in 50 mM phosphate buffer for Alpha-2 adrenergic receptor | Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ05ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50013515 ((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank | n/a | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dissociation constant in low affinity sites where the binding is in 50 mM phosphate buffer for Alpha-2 adrenergic receptor | Citation and Details BindingDB Entry DOI: 10.7270/Q2WQ05ZJ | |||||||||||
More data for this Ligand-Target Pair |