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Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor' and Ligand = 'BDBM50008786'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor


(RAT-NEONATAL RAT-Rattus norvegicus (rat))		BDBM50008786
PNG
(CHEMBL43506 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-...)
Show SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(CCF)cc(OC)c1OC
Show InChI InChI=1S/C18H27FN2O4/c1-4-21-9-5-6-13(21)11-20-18(23)15-16(22)12(7-8-19)10-14(24-2)17(15)25-3/h10,13,22H,4-9,11H2,1-3H3,(H,20,23)/t13-/m0/s1
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 9.5n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
binding affinity towards alpha-2 adrenergic receptor, using [3H]- atipamezole as radioligand from rat frontal cortex membranes

J Med Chem 34: 1612-24 (1991)


BindingDB Entry DOI: 10.7270/Q2GH9GXF
More data for this
Ligand-Target Pair