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Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor' and Ligand = 'BDBM50226845'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor


(RAT-NEONATAL RAT-Rattus norvegicus (rat))		BDBM50226845
PNG
(CHEMBL269537)
Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCC(CC(=O)NCC2CC2)CC1
Show InChI InChI=1S/C21H29N5O3/c1-28-17-10-15-16(11-18(17)29-2)24-21(25-20(15)22)26-7-5-13(6-8-26)9-19(27)23-12-14-3-4-14/h10-11,13-14H,3-9,12H2,1-2H3,(H,23,27)(H2,22,24,25)
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PC sid
UniChem

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PubMed
 53n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity determined for alpha-2 adrenergic receptor by the percentage displacement of [3H]- clonidine at 10e-6 M

J Med Chem 30: 999-1003 (1987)


BindingDB Entry DOI: 10.7270/Q2PC34MG
More data for this
Ligand-Target Pair