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Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-2C adrenergic receptor' and Ligand = 'BDBM398516'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-2C adrenergic receptor


(Homo sapiens (Human))		BDBM398516
PNG
(US10323020, Example 10 | [4-(6-Methoxy-3,4-dihydro...)
Show SMILES COc1ccc2CN(CCc2c1)C1CCN(CC1)C(=O)c1cnc(nc1)N1CC2(COC2)C1
Show InChI InChI=1S/C25H31N5O3/c1-32-22-3-2-19-13-29(7-4-18(19)10-22)21-5-8-28(9-6-21)23(31)20-11-26-24(27-12-20)30-14-25(15-30)16-33-17-25/h2-3,10-12,21H,4-9,13-17H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 30n/an/an/an/an/an/a



The Scripps Research Institute



Assay Description
Antagonism against the adrenoreceptor α1A was tested using a recombinant human α1A receptor CHO cell line which additionally also recombina...

Bioorg Med Chem Lett 19: 3344-7 (2009)


BindingDB Entry DOI: 10.7270/Q2PN9803
More data for this
Ligand-Target Pair