Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50473226 (CHEMBL297827) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc. Curated by ChEMBL | Assay Description Inhibitory constant, using [3H]rauwolscine in LM(tk-) cells stably transfected with cloned human Alpha-2C adrenergic receptor | J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2C adrenergic receptor (Homo sapiens (Human)) | BDBM50473226 (CHEMBL297827) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Lundbeck Research USA, Inc. Curated by ChEMBL | Assay Description Alpha2c receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMP | J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4 | |||||||||||
More data for this Ligand-Target Pair |