Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (Homo sapiens (Human)) | BDBM50463170 (CHEMBL4239759) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Indian Institute of Technology Hyderabad Curated by ChEMBL | Assay Description Inhibition of recombinant human AlkBH3 assessed as reduction in formaldehyde release using 40-mer single N3-meC as substrate incubated for 60 mins fo... | Bioorg Med Chem 26: 4100-4112 (2018) Article DOI: 10.1016/j.bmc.2018.06.040 BindingDB Entry DOI: 10.7270/Q22B91PG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (Homo sapiens (Human)) | BDBM50463170 (CHEMBL4239759) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 7.81E+3 | n/a | n/a | n/a | n/a | n/a |
Indian Institute of Technology Hyderabad Curated by ChEMBL | Assay Description Binding affinity to recombinant human AlkBH3 incubated for 2 mins by isothermal titration calorimetric method | Bioorg Med Chem 26: 4100-4112 (2018) Article DOI: 10.1016/j.bmc.2018.06.040 BindingDB Entry DOI: 10.7270/Q22B91PG | |||||||||||
More data for this Ligand-Target Pair |