Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Alpha-synuclein' and Ligand = 'BDBM481153'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-synuclein (Homo sapiens (Human))	BDBM481153 (US10906900, Reference 22f) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccc(F)nc2[nH]1 Show InChI InChI=1S/C17H14FN3/c1-21(2)15-8-4-12(5-9-15)3-7-14-11-13-6-10-16(18)20-17(13)19-14/h4-6,8-11H,1-2H3,(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	14.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM481153 (US10906900, Reference 22f) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccc(F)nc2[nH]1 Show InChI InChI=1S/C17H14FN3/c1-21(2)15-8-4-12(5-9-15)3-7-14-11-13-6-10-16(18)20-17(13)19-14/h4-6,8-11H,1-2H3,(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.790	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair