Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Amiloride-sensitive sodium channel subunit alpha (Homo sapiens (Human)) | BDBM50190456 (CHEMBL209659 | N-(3,5-diamino-6-chloropyrazine-2-c...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Parion Sciences Inc. Curated by ChEMBL | Assay Description Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assay | J Med Chem 49: 4098-115 (2006) Article DOI: 10.1021/jm051134w BindingDB Entry DOI: 10.7270/Q2FT8KNH | |||||||||||
More data for this Ligand-Target Pair |