Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat)) | BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using PEA as substrate preincubated for 60 mins | Citation and Details Article DOI: 10.1016/j.bmc.2020.115888 BindingDB Entry DOI: 10.7270/Q2057KM3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat)) | BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Competitive inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using PEA as substrate by Lineweaver-Burk plot analysis | Citation and Details Article DOI: 10.1016/j.bmc.2020.115888 BindingDB Entry DOI: 10.7270/Q2057KM3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat)) | BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using [14C]-PEA as substrate preincubated for 60 mins by radiochemical method | Citation and Details Article DOI: 10.1016/j.bmc.2020.115888 BindingDB Entry DOI: 10.7270/Q2057KM3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat)) | BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Sprague-Dawley rat brain mitochondrial MAO-B using [14C]-PEA as substrate preincubated for 120 mins by radiochemical method | Citation and Details Article DOI: 10.1016/j.bmc.2020.115888 BindingDB Entry DOI: 10.7270/Q2057KM3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat)) | BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Paris 7 Curated by ChEMBL | Assay Description Compound was evaluated for the time-dependence inhibition of MAO-B at 60 minutes preincubation periods | J Med Chem 36: 1157-67 (1993) BindingDB Entry DOI: 10.7270/Q2765FZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat)) | BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Paris 7 Curated by ChEMBL | Assay Description In vitro inhibitory activity on rat brain MAO-B. | J Med Chem 36: 1157-67 (1993) BindingDB Entry DOI: 10.7270/Q2765FZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat)) | BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Paris 7 Curated by ChEMBL | Assay Description Compound was evaluated for the time-dependence inhibition of MAO-B at 30 minutes pre-incubation periods | J Med Chem 36: 1157-67 (1993) BindingDB Entry DOI: 10.7270/Q2765FZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Facultés Universitaires Notre-Dame de la Paix Curated by ChEMBL | Assay Description Inhibitory concentration against Monoamine oxidase B was measured in baboon liver. | Bioorg Med Chem Lett 13: 69-73 (2002) BindingDB Entry DOI: 10.7270/Q2WM1CRP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat)) | BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Paris 7 Curated by ChEMBL | Assay Description Compound was evaluated for the time-dependence inhibition of MAO-B at 20 minutes pre-incubation periods | J Med Chem 36: 1157-67 (1993) BindingDB Entry DOI: 10.7270/Q2765FZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01571 BindingDB Entry DOI: 10.7270/Q25H7MBX | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat)) | BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Paris 7 Curated by ChEMBL | Assay Description Compound was evaluated for the Inhibition of Monoamine oxidase B | J Med Chem 38: 4786-92 (1996) BindingDB Entry DOI: 10.7270/Q2T72GFV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat)) | BDBM50029825 (3-[5-(4-Benzyloxy-phenyl)-2-oxo-[1,3,4]oxadiazol-3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Paris 7 Curated by ChEMBL | Assay Description Compound was evaluated for the time-dependence inhibition of MAO-B at 0 minute pre-incubation periods | J Med Chem 36: 1157-67 (1993) BindingDB Entry DOI: 10.7270/Q2765FZP | |||||||||||
More data for this Ligand-Target Pair |