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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Aminopeptidase N' and Ligand = 'BDBM50210534'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50210534
PNG
((S)-methyl 2-(2-((S)-2,6-dioxo-3-(3,4,5-trimethoxy...)
Show SMILES COC(=O)[C@H](CCCNC(N)=N[N+]([O-])=O)NC(=O)CN1C(=O)CC[C@H](NC(=O)c2cc(OC)c(OC)c(OC)c2)C1=O |w:11.11|
Show InChI InChI=1S/C24H33N7O11/c1-39-16-10-13(11-17(40-2)20(16)41-3)21(34)28-14-7-8-19(33)30(22(14)35)12-18(32)27-15(23(36)42-4)6-5-9-26-24(25)29-31(37)38/h10-11,14-15H,5-9,12H2,1-4H3,(H,27,32)(H,28,34)(H3,25,26,29)/t14-,15-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.20E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomes aminopeptidase N preincubated for 30 mins


Eur J Med Chem 44: 4819-25 (2009)


Article DOI: 10.1016/j.ejmech.2009.07.022
BindingDB Entry DOI: 10.7270/Q2251J73
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50210534
PNG
((S)-methyl 2-(2-((S)-2,6-dioxo-3-(3,4,5-trimethoxy...)
Show SMILES COC(=O)[C@H](CCCNC(N)=N[N+]([O-])=O)NC(=O)CN1C(=O)CC[C@H](NC(=O)c2cc(OC)c(OC)c(OC)c2)C1=O |w:11.11|
Show InChI InChI=1S/C24H33N7O11/c1-39-16-10-13(11-17(40-2)20(16)41-3)21(34)28-14-7-8-19(33)30(22(14)35)12-18(32)27-15(23(36)42-4)6-5-9-26-24(25)29-31(37)38/h10-11,14-15H,5-9,12H2,1-4H3,(H,27,32)(H,28,34)(H3,25,26,29)/t14-,15-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.20E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomal aminopeptidase assessed as liberation of p-nitroanilide


Bioorg Med Chem Lett 17: 2935-8 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.095
BindingDB Entry DOI: 10.7270/Q2HT2P11
More data for this
Ligand-Target Pair