Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM145844'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM145844 (US8956589, 6) Show SMILES COC(=O)CCCC(C(=O)\C=C\c1ccc(O)c(OC(F)(F)F)c1)C(=O)\C=C\c1ccc(O)c(OC(F)(F)F)c1 Show InChI InChI=1S/C26H22F6O8/c1-38-24(37)4-2-3-17(18(33)9-5-15-7-11-20(35)22(13-15)39-25(27,28)29)19(34)10-6-16-8-12-21(36)23(14-16)40-26(30,31)32/h5-14,17,35-36H,2-4H2,1H3/b9-5+,10-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	310	n/a	n/a	n/a	n/a	7.5	30
Shiga University of Medical Science US Patent					Assay Description First, amyloid beta peptides (1-40, Peptide Institute, Minoh-shi, Osaka) were dissolved in a 50 mM phosphate buffer containing 100 mM sodium chloride...				US Patent US8956589 (2015) BindingDB Entry DOI: 10.7270/Q2BG2MQ5
					More data for this Ligand-Target Pair