Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM50173645'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50173645 (4-Methoxy-benzenesulfonic acid 3-{4-[(E)-2-(4-dime...) Show SMILES COc1ccc(cc1)S(=O)(=O)OCC(CO)COc1ccc(\C=C\c2ccc(cc2)N(C)C)cc1 Show InChI InChI=1S/C27H31NO6S/c1-28(2)24-10-6-21(7-11-24)4-5-22-8-12-26(13-9-22)33-19-23(18-29)20-34-35(30,31)27-16-14-25(32-3)15-17-27/h4-17,23,29H,18-20H2,1-3H3/b5-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition constant for I-125-IMPY binding to amyloid plaques in Alzheimers disease brain homogenates				J Med Chem 48: 5980-8 (2005) Article DOI: 10.1021/jm050166g BindingDB Entry DOI: 10.7270/Q2TB17PR
					More data for this Ligand-Target Pair