Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM50476278'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476278 (CHEMBL224149) Show SMILES CNc1ccc(\C=C\c2cnc(OCCO)c(I)c2)cc1 Show InChI InChI=1S/C16H17IN2O2/c1-18-14-6-4-12(5-7-14)2-3-13-10-15(17)16(19-11-13)21-9-8-20/h2-7,10-11,18,20H,8-9H2,1H3/b3-2+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [15I]IMPY from Abeta peptide plaques in Alzheimer's disease patient brain				J Med Chem 50: 2157-65 (2007) Article DOI: 10.1021/jm070025+ BindingDB Entry DOI: 10.7270/Q21N83WD
					More data for this Ligand-Target Pair