Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM50476284'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476284 (CHEMBL227869) Show SMILES CN(C)c1ccc(\C=C\c2cnc(OCCOCCOCCF)c(Br)c2)cc1 Show InChI InChI=1S/C21H26BrFN2O3/c1-25(2)19-7-5-17(6-8-19)3-4-18-15-20(22)21(24-16-18)28-14-13-27-12-11-26-10-9-23/h3-8,15-16H,9-14H2,1-2H3/b4-3+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [15I]IMPY from Abeta peptide plaques in Alzheimer's disease patient brain				J Med Chem 50: 2157-65 (2007) Article DOI: 10.1021/jm070025+ BindingDB Entry DOI: 10.7270/Q21N83WD
					More data for this Ligand-Target Pair