Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM50491255'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50491255 (CHEMBL2381386) Show SMILES COc1ccc2cc(C(=O)CN3CCC(Cc4ccccc4)CC3)c(=O)oc2c1 Show InChI InChI=1S/C24H25NO4/c1-28-20-8-7-19-14-21(24(27)29-23(19)15-20)22(26)16-25-11-9-18(10-12-25)13-17-5-3-2-4-6-17/h2-8,14-15,18H,9-13,16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Boston Curated by ChEMBL					Assay Description Inhibition of amyloid beta ((1 to 42) (unknown origin) oligomer assembly after 30 mins by biotinyl-streptavidin assay				Bioorg Med Chem Lett 23: 2614-8 (2013) Article DOI: 10.1016/j.bmcl.2013.02.103 BindingDB Entry DOI: 10.7270/Q27M0BWS
					More data for this Ligand-Target Pair