Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Angiopoietin-1 receptor' and Ligand = 'BDBM50230174'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50230174 (CHEMBL4085495) Show SMILES Nc1n[nH]c2cccc(-c3cccc(NC(=O)C4(CC4)C(=O)Nc4cc(Br)cc(c4)C(F)(F)F)c3)c12 Show InChI InChI=1S/C25H19BrF3N5O2/c26-15-10-14(25(27,28)29)11-17(12-15)32-23(36)24(7-8-24)22(35)31-16-4-1-3-13(9-16)18-5-2-6-19-20(18)21(30)34-33-19/h1-6,9-12H,7-8H2,(H,31,35)(H,32,36)(H3,30,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of TIE-2 (unknown origin) after 60 mins by ADP-Glo assay				Eur J Med Chem 127: 275-285 (2017) Article DOI: 10.1016/j.ejmech.2016.12.059 BindingDB Entry DOI: 10.7270/Q2XW4N27
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