BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Angiopoietin-1 receptor' and Ligand = 'BDBM50311975'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiopoietin-1 receptor


(Homo sapiens (Human))
BDBM50311975
PNG
(2-(1-isobutyl-4-phenyl-1H-imidazol-5-yl)thiazolo[5...)
Show SMILES CC(C)Cn1cnc(c1-c1nc2c(N)ncnc2s1)-c1ccccc1
Show InChI InChI=1S/C18H18N6S/c1-11(2)8-24-10-22-13(12-6-4-3-5-7-12)15(24)18-23-14-16(19)20-9-21-17(14)25-18/h3-7,9-11H,8H2,1-2H3,(H2,19,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 490n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of Tie-2 phosphorylation by cell based assay


Bioorg Med Chem Lett 19: 6670-4 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.001
BindingDB Entry DOI: 10.7270/Q2FN16BJ
More data for this
Ligand-Target Pair