Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Angiopoietin-1 receptor [776-1124]' and Ligand = 'BDBM239653'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor [776-1124] (Homo sapiens (Human))	BDBM239653 (US9394309, 109) Show SMILES Cc1cc(C)c(cc1NC(=O)c1cc(Br)cc(c1)S(F)(F)(F)(F)F)-n1ccn2nc(cc12)-c1cccnc1 Show InChI InChI=1S/C25H19BrF5N5OS/c1-15-8-16(2)23(35-6-7-36-24(35)13-22(34-36)17-4-3-5-32-14-17)12-21(15)33-25(37)18-9-19(26)11-20(10-18)38(27,28,29,30)31/h3-14H,1-2H3,(H,33,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	7.0	22
Bayer Pharma Aktiengesellschaft; Bayer Intellectual Property GmbH US Patent					Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr...				US Patent US9394309 (2016) BindingDB Entry DOI: 10.7270/Q2C53JRC
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