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Found 1 hit Enz. Inhib. hit(s) with Target = 'Angiotensin-converting enzyme' and Ligand = 'BDBM50024714'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Angiotensin-converting enzyme


(Oryctolagus cuniculus)		BDBM50024714
PNG
(2-(4-Carboxymethyl-5-oxo-3-thiophen-2-yl-[1,4]thia...)
Show SMILES OC(=O)CN1C(CSC[C@H](N[C@@H](CCc2ccccc2)C(O)=O)C1=O)c1cccs1
Show InChI InChI=1S/C21H24N2O5S2/c24-19(25)11-23-17(18-7-4-10-30-18)13-29-12-16(20(23)26)22-15(21(27)28)9-8-14-5-2-1-3-6-14/h1-7,10,15-17,22H,8-9,11-13H2,(H,24,25)(H,27,28)/t15-,16-,17?/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 2.80n/an/an/an/an/an/a



Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrate

J Med Chem 30: 1984-91 (1987)


BindingDB Entry DOI: 10.7270/Q2Q52NMJ
More data for this
Ligand-Target Pair