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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Anoctamin-2' and Ligand = 'BDBM50239457'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Anoctamin-2


(Homo sapiens)		BDBM50239457
PNG
(CHEMBL4071143)
Show SMILES Cc1ccccc1NC(=O)c1c(NC(=O)C(F)(F)Cl)sc2CCCCCc12
Show InChI InChI=1S/C19H19ClF2N2O2S/c1-11-7-5-6-9-13(11)23-16(25)15-12-8-3-2-4-10-14(12)27-17(15)24-18(26)19(20,21)22/h5-7,9H,2-4,8,10H2,1H3,(H,23,25)(H,24,26)
UniProtKB/SwissProt

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PC sid
UniChem

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Article
PubMed
n/an/a 400n/an/an/an/an/an/a



San Francisco State University

Curated by ChEMBL


Assay Description
Inhibition of human TMEM16B expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...

J Med Chem 60: 4626-4635 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00020
BindingDB Entry DOI: 10.7270/Q2FT8P5G
More data for this
Ligand-Target Pair