Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM177786 (US9120791, Example 1 | US9120791, Example 38 | US9...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tsinghua University Curated by ChEMBL | Assay Description Inhibition of Bcl2 (unknown origin) after 2 hrs by fluorescein-PUMA based fluorescence polarization assay | Eur J Med Chem 177: 63-75 (2019) Article DOI: 10.1016/j.ejmech.2019.05.019 BindingDB Entry DOI: 10.7270/Q2R78JMK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM177786 (US9120791, Example 1 | US9120791, Example 38 | US9...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114184 BindingDB Entry DOI: 10.7270/Q2M049DT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM177786 (US9120791, Example 1 | US9120791, Example 38 | US9...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114184 BindingDB Entry DOI: 10.7270/Q2M049DT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM177786 (US9120791, Example 1 | US9120791, Example 38 | US9...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114184 BindingDB Entry DOI: 10.7270/Q2M049DT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM177786 (US9120791, Example 1 | US9120791, Example 38 | US9...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114184 BindingDB Entry DOI: 10.7270/Q2M049DT | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM177786 (US9120791, Example 1 | US9120791, Example 38 | US9...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is... | US Patent US9603854 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Mus musculus (Mouse)) | BDBM177786 (US9120791, Example 1 | US9120791, Example 38 | US9...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 18 | n/a | n/a | n/a | n/a | 7.4 | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is... | US Patent US9120791 (2015) BindingDB Entry DOI: 10.7270/Q21N7ZWC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM177786 (US9120791, Example 1 | US9120791, Example 38 | US9...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is... | US Patent US9603854 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Mus musculus (Mouse)) | BDBM177786 (US9120791, Example 1 | US9120791, Example 38 | US9...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | 7.4 | n/a |
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent | Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is... | US Patent US9120791 (2015) BindingDB Entry DOI: 10.7270/Q21N7ZWC | |||||||||||
More data for this Ligand-Target Pair |