Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM177799'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM177799 (US9120791, Example 17 | US9603854, 17) Show SMILES C[C@H]1COC[C@H](C)N1C[C@@H]1Cc2ccccc2CN1C(=O)c1cc2OCOc2cc1-c1cc(C(=O)N(c2ccc(O)cc2)c2ccc3n(C)ccc3c2)c2CCCCn12 Show InChI InChI=1S/C48H49N5O6/c1-30-27-57-28-31(2)51(30)26-37-20-32-8-4-5-9-34(32)25-52(37)47(55)40-24-46-45(58-29-59-46)23-39(40)44-22-41(43-10-6-7-18-50(43)44)48(56)53(35-11-14-38(54)15-12-35)36-13-16-42-33(21-36)17-19-49(42)3/h4-5,8-9,11-17,19,21-24,30-31,37,54H,6-7,10,18,20,25-29H2,1-3H3/t30-,31-,37-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9603854 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DMT
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Mus musculus (Mouse))	BDBM177799 (US9120791, Example 17 | US9603854, 17) Show SMILES C[C@H]1COC[C@H](C)N1C[C@@H]1Cc2ccccc2CN1C(=O)c1cc2OCOc2cc1-c1cc(C(=O)N(c2ccc(O)cc2)c2ccc3n(C)ccc3c2)c2CCCCn12 Show InChI InChI=1S/C48H49N5O6/c1-30-27-57-28-31(2)51(30)26-37-20-32-8-4-5-9-34(32)25-52(37)47(55)40-24-46-45(58-29-59-46)23-39(40)44-22-41(43-10-6-7-18-50(43)44)48(56)53(35-11-14-38(54)15-12-35)36-13-16-42-33(21-36)17-19-49(42)3/h4-5,8-9,11-17,19,21-24,30-31,37,54H,6-7,10,18,20,25-29H2,1-3H3/t30-,31-,37-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	81	n/a	n/a	n/a	n/a	7.4	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9120791 (2015) BindingDB Entry DOI: 10.7270/Q21N7ZWC
					More data for this Ligand-Target Pair