Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM177807'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM177807 (US9120791, Example 25 | US9603854, 25) Show SMILES Oc1ccc(cc1)N(C(=O)c1cc(-c2cc(F)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccccc1 Show InChI InChI=1S/C42H41FN4O4/c43-31-13-18-36(41(49)46-27-30-9-5-4-8-29(30)24-34(46)28-44-20-22-51-23-21-44)37(25-31)40-26-38(39-12-6-7-19-45(39)40)42(50)47(32-10-2-1-3-11-32)33-14-16-35(48)17-15-33/h1-5,8-11,13-18,25-26,34,48H,6-7,12,19-24,27-28H2/t34-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9603854 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DMT
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Mus musculus (Mouse))	BDBM177807 (US9120791, Example 25 | US9603854, 25) Show SMILES Oc1ccc(cc1)N(C(=O)c1cc(-c2cc(F)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccccc1 Show InChI InChI=1S/C42H41FN4O4/c43-31-13-18-36(41(49)46-27-30-9-5-4-8-29(30)24-34(46)28-44-20-22-51-23-21-44)37(25-31)40-26-38(39-12-6-7-19-45(39)40)42(50)47(32-10-2-1-3-11-32)33-14-16-35(48)17-15-33/h1-5,8-11,13-18,25-26,34,48H,6-7,12,19-24,27-28H2/t34-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	7.4	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9120791 (2015) BindingDB Entry DOI: 10.7270/Q21N7ZWC
					More data for this Ligand-Target Pair