Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM177865'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM177865 (US9120791, Example 87 | US9603854, 87) Show SMILES CCCCN(C(=O)c1cc(-c2cc3OCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccc(O)cc1 Show InChI InChI=1S/C41H46N4O6/c1-2-3-15-43(30-11-13-32(46)14-12-30)41(48)35-22-37(44-16-7-6-10-36(35)44)33-23-38-39(51-27-50-38)24-34(33)40(47)45-25-29-9-5-4-8-28(29)21-31(45)26-42-17-19-49-20-18-42/h4-5,8-9,11-14,22-24,31,46H,2-3,6-7,10,15-21,25-27H2,1H3/t31-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9603854 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DMT
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Mus musculus (Mouse))	BDBM177865 (US9120791, Example 87 | US9603854, 87) Show SMILES CCCCN(C(=O)c1cc(-c2cc3OCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccc(O)cc1 Show InChI InChI=1S/C41H46N4O6/c1-2-3-15-43(30-11-13-32(46)14-12-30)41(48)35-22-37(44-16-7-6-10-36(35)44)33-23-38-39(51-27-50-38)24-34(33)40(47)45-25-29-9-5-4-8-28(29)21-31(45)26-42-17-19-49-20-18-42/h4-5,8-9,11-14,22-24,31,46H,2-3,6-7,10,15-21,25-27H2,1H3/t31-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	7.4	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9120791 (2015) BindingDB Entry DOI: 10.7270/Q21N7ZWC
					More data for this Ligand-Target Pair