Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM177881'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM177881 (US9120791, Example 110 | US9603854, 110) Show SMILES CCN(CCOC)C[C@@H]1Cc2ccccc2CN1C(=O)c1ccc(Cl)cc1-c1cc(C(=O)N(c2ccc(O)cc2)c2ccc3n(C)ccc3c2)c2CCCCn12 Show InChI InChI=1S/C46H48ClN5O4/c1-4-49(23-24-56-3)30-37-25-31-9-5-6-10-33(31)29-51(37)45(54)39-18-12-34(47)27-40(39)44-28-41(43-11-7-8-21-50(43)44)46(55)52(35-13-16-38(53)17-14-35)36-15-19-42-32(26-36)20-22-48(42)2/h5-6,9-10,12-20,22,26-28,37,53H,4,7-8,11,21,23-25,29-30H2,1-3H3/t37-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9603854 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DMT
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Mus musculus (Mouse))	BDBM177881 (US9120791, Example 110 | US9603854, 110) Show SMILES CCN(CCOC)C[C@@H]1Cc2ccccc2CN1C(=O)c1ccc(Cl)cc1-c1cc(C(=O)N(c2ccc(O)cc2)c2ccc3n(C)ccc3c2)c2CCCCn12 Show InChI InChI=1S/C46H48ClN5O4/c1-4-49(23-24-56-3)30-37-25-31-9-5-6-10-33(31)29-51(37)45(54)39-18-12-34(47)27-40(39)44-28-41(43-11-7-8-21-50(43)44)46(55)52(35-13-16-38(53)17-14-35)36-15-19-42-32(26-36)20-22-48(42)2/h5-6,9-10,12-20,22,26-28,37,53H,4,7-8,11,21,23-25,29-30H2,1-3H3/t37-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	7.4	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9120791 (2015) BindingDB Entry DOI: 10.7270/Q21N7ZWC
					More data for this Ligand-Target Pair