Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM179564'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179564 (US9126980, 9) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccc(cc2)-c2ccc(Cl)cc2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C42H46ClN5O4S/c1-4-6-22-46(23-7-5-2)42(51)39-24-29(3)48(44-39)40-21-18-35(45-53(52)37-19-14-31(15-20-37)30-12-16-34(43)17-13-30)26-38(40)41(50)47-27-33-11-9-8-10-32(33)25-36(47)28-49/h8-21,24,26,36,45,49H,4-7,22-23,25,27-28H2,1-3H3/t36-,53?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM179564 (US9126980, 9) Show SMILES CCCCN(CCCC)C(=O)c1cc(C)n(n1)-c1ccc(NS(=O)c2ccc(cc2)-c2ccc(Cl)cc2)cc1C(=O)N1Cc2ccccc2C[C@H]1CO |r| Show InChI InChI=1S/C42H46ClN5O4S/c1-4-6-22-46(23-7-5-2)42(51)39-24-29(3)48(44-39)40-21-18-35(45-53(52)37-19-14-31(15-20-37)30-12-16-34(43)17-13-30)26-38(40)41(50)47-27-33-11-9-8-10-32(33)25-36(47)28-49/h8-21,24,26,36,45,49H,4-7,22-23,25,27-28H2,1-3H3/t36-,53?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Methods for Determining IC50s.The present method includes utility of a Surface plasmon resonance (SPR)- based biosensor (Biacore GE Healthcare, Uppsa...				US Patent US9126980 (2015) BindingDB Entry DOI: 10.7270/Q2S18184
					More data for this Ligand-Target Pair