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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM340980'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM340980
PNG
(N-(4-Fluorophenyl)-N-(4-hydroxyphenyl)-1-(6-{[(3S)...)
Show SMILES CN1CCN(C[C@@H]2Cc3ccccc3CN2C(=O)c2cc3OCOc3cc2-n2cc(C(=O)N(c3ccc(O)cc3)c3ccc(F)cc3)c3ccccc23)CC1
Show InChI InChI=1S/C44H40FN5O5/c1-46-18-20-47(21-19-46)26-34-22-29-6-2-3-7-30(29)25-48(34)43(52)37-23-41-42(55-28-54-41)24-40(37)49-27-38(36-8-4-5-9-39(36)49)44(53)50(32-12-10-31(45)11-13-32)33-14-16-35(51)17-15-33/h2-17,23-24,27,34,51H,18-22,25-26,28H2,1H3/t34-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 3.5n/an/an/an/an/an/a



LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent


Assay Description
Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...

US Patent US9765056 (2017)


BindingDB Entry DOI: 10.7270/Q2T72KJF
More data for this
Ligand-Target Pair