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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM341037'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM341037
PNG
(N-(4-Hydroxyphenyl)-5-methyl-N-(1-methyl-1H-indol-...)
Show SMILES CN1CCN(C[C@@H]2Cc3ccccc3CN2C(=O)c2cc3OCOc3cc2-n2cc(cc2C)C(=O)N(c2ccc(O)cc2)c2ccc3n(C)ccc3c2)CC1
Show InChI InChI=1S/C44H44N6O5/c1-29-20-33(43(52)50(34-8-11-37(51)12-9-34)35-10-13-39-31(22-35)14-15-46(39)3)26-48(29)40-24-42-41(54-28-55-42)23-38(40)44(53)49-25-32-7-5-4-6-30(32)21-36(49)27-47-18-16-45(2)17-19-47/h4-15,20,22-24,26,36,51H,16-19,21,25,27-28H2,1-3H3/t36-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 3.60n/an/an/an/an/an/a



LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent


Assay Description
Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...

US Patent US9765056 (2017)


BindingDB Entry DOI: 10.7270/Q2T72KJF
More data for this
Ligand-Target Pair