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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM341098'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM341098
PNG
(1-{4-Hydroxy-5-methoxy-2-[(3S)-3-[(4-methylpiperaz...)
Show SMILES COc1cc(c(cc1O)C(=O)N1Cc2ccccc2C[C@H]1CN1CCN(C)CC1)-n1cc(C(=O)N(c2ccccc2)c2ccc(O)cc2)c2ccccc12
Show InChI InChI=1S/C44H43N5O5/c1-45-20-22-46(23-21-45)28-34-24-30-10-6-7-11-31(30)27-47(34)43(52)37-25-41(51)42(54-2)26-40(37)48-29-38(36-14-8-9-15-39(36)48)44(53)49(32-12-4-3-5-13-32)33-16-18-35(50)19-17-33/h3-19,25-26,29,34,50-51H,20-24,27-28H2,1-2H3/t34-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 3.20n/an/an/an/an/an/a



LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent


Assay Description
Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...

US Patent US9765056 (2017)


BindingDB Entry DOI: 10.7270/Q2T72KJF
More data for this
Ligand-Target Pair