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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM353043'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM353043
PNG
(N,1,2-Trimethyl-5-{7-[(3R)-3-methyl-1,2,3,4-tetrah...)
Show SMILES C[C@@H]1Cc2ccccc2CN1C(=O)c1cc2CN(CCc2cc1-c1cc(C(=O)N(C)c2ccccc2)c(C)n1C)C(=O)Cc1ccccc1
Show InChI InChI=1S/C42H42N4O3/c1-28-21-31-15-11-12-16-33(31)27-46(28)42(49)38-24-34-26-45(40(47)22-30-13-7-5-8-14-30)20-19-32(34)23-37(38)39-25-36(29(2)43(39)3)41(48)44(4)35-17-9-6-10-18-35/h5-18,23-25,28H,19-22,26-27H2,1-4H3/t28-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 3.40n/an/an/an/an/an/a



LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent


Assay Description
The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...

US Patent US9809574 (2017)


BindingDB Entry DOI: 10.7270/Q2MP55DF
More data for this
Ligand-Target Pair