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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM354588'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM354588
PNG
(Phenyl 6-{4-[(4-hydroxyphenyl)(propyl)carbamoyl]-1...)
Show SMILES CCCN(C(=O)c1cc(-c2cc3CCN(Cc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)C(=O)Oc2ccccc2)n(C)c1C)c1ccc(O)cc1
Show InChI InChI=1S/C47H51N5O6/c1-4-19-51(37-14-16-39(53)17-15-37)45(54)41-28-44(48(3)32(41)2)42-26-34-18-20-50(47(56)58-40-12-6-5-7-13-40)29-36(34)27-43(42)46(55)52-30-35-11-9-8-10-33(35)25-38(52)31-49-21-23-57-24-22-49/h5-17,26-28,38,53H,4,18-25,29-31H2,1-3H3/t38-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 2.5n/an/an/an/an/an/a



LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent


Assay Description
The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...

US Patent US9809574 (2017)


BindingDB Entry DOI: 10.7270/Q2MP55DF
More data for this
Ligand-Target Pair