Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM50127855'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50127855 (CHEMBL3628073) Show SMILES CC(=O)c1ccc(cc1)N1C(=S)S\C(=C/c2ccc(OCc3ccc(cc3)C(O)=O)cc2)C1=O Show InChI InChI=1S/C26H19NO5S2/c1-16(28)19-8-10-21(11-9-19)27-24(29)23(34-26(27)33)14-17-4-12-22(13-5-17)32-15-18-2-6-20(7-3-18)25(30)31/h2-14H,15H2,1H3,(H,30,31)/b23-14-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of Bcl-2 (unknown origin) by fluorescence polarization assay				Bioorg Med Chem Lett 25: 5265-9 (2015) Article DOI: 10.1016/j.bmcl.2015.09.051 BindingDB Entry DOI: 10.7270/Q2RB76DD
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