Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM50202270'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50202270 (2-propenyl 2-[5-(4-bromobenzylidene)-4-oxo-2-thiox...) Show SMILES Brc1ccc(\C=C2/SC(=S)N([C@@H](Cc3ccccc3)C(=O)OCC=C)C2=O)cc1 Show InChI InChI=1S/C22H18BrNO3S2/c1-2-12-27-21(26)18(13-15-6-4-3-5-7-15)24-20(25)19(29-22(24)28)14-16-8-10-17(23)11-9-16/h2-11,14,18H,1,12-13H2/b19-14-/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl2 protein by fluorescence polarization assay				Bioorg Med Chem 15: 2167-76 (2007) Article DOI: 10.1016/j.bmc.2006.12.020 BindingDB Entry DOI: 10.7270/Q28W3F4C
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