Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM50254528'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50254528 ((3S)-ethyl 2-(2-(3-(diphenylcarbamoyl)-5-methyl-1H...) Show SMILES CCOC(=O)[C@@H]1Cc2ccccc2CN1C(=O)c1ccccc1-n1nc(cc1C)C(=O)N(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C36H32N4O4/c1-3-44-36(43)33-23-26-14-10-11-15-27(26)24-38(33)34(41)30-20-12-13-21-32(30)40-25(2)22-31(37-40)35(42)39(28-16-6-4-7-17-28)29-18-8-5-9-19-29/h4-22,33H,3,23-24H2,1-2H3/t33-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 16 mer Bak-BH3 peptide by HTRF-LANCE assay				Bioorg Med Chem Lett 19: 230-3 (2008) Article DOI: 10.1016/j.bmcl.2008.10.113 BindingDB Entry DOI: 10.7270/Q29023MG
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