Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM50441890'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50441890 (CHEMBL2436890) Show SMILES Oc1cc2c(nc(-c3ccccc3)n(Cc3ccccc3)c2=O)c(O)c1O Show InChI InChI=1S/C21H16N2O4/c24-16-11-15-17(19(26)18(16)25)22-20(14-9-5-2-6-10-14)23(21(15)27)12-13-7-3-1-4-8-13/h1-11,24-26H,12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	959	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalian University of Technology Curated by ChEMBL					Assay Description Displacement of FAM-Bid BH3 peptide from recombinant Bcl-2 (unknown origin) expressed in Escherichia coli BL21 after 10 mins by fluorescence polariza...				Eur J Med Chem 69: 711-8 (2013) Article DOI: 10.1016/j.ejmech.2013.09.030 BindingDB Entry DOI: 10.7270/Q2348MT5
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