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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM50541342'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM50541342
PNG
(CHEMBL4645693)
Show SMILES [#6]-[#8]-c1ccc(-[#7]-[#6](=O)-[#6@@H]-2-[#6]-[#6]=[#6](-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6@H]-2-c2ccccc2)cc1 |r,t:11|
Show InChI InChI=1S/C26H31NO2/c1-19(2)8-7-9-20-12-17-24(25(18-20)21-10-5-4-6-11-21)26(28)27-22-13-15-23(29-3)16-14-22/h4-6,8,10-16,24-25H,7,9,17-18H2,1-3H3,(H,27,28)/t24-,25+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
>2.30E+4n/an/an/an/an/an/an/an/a



Universit£ Paris-Saclay

Curated by ChEMBL


Assay Description
Inhibition of Bcl2 (unknown origin)/Bim interaction preincubated for 5 mins followed by fluorescein-labeled peptide addition and measured after 10 mi...

Bioorg Med Chem Lett 30: (2020)


Article DOI: 10.1016/j.bmcl.2020.127003
BindingDB Entry DOI: 10.7270/Q2445R24
More data for this
Ligand-Target Pair