Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Arachidonate 5-lipoxygenase-activating protein' and Ligand = 'BDBM167143'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM167143 (US9073876, 225 | US9732093, Compound 225) Show SMILES Fc1c(Oc2ncccn2)c(ccc1-c1cnc2NCCOc2c1)C1CCC1 Show InChI InChI=1S/C21H19FN4O2/c22-18-15(14-11-17-20(26-12-14)23-9-10-27-17)5-6-16(13-3-1-4-13)19(18)28-21-24-7-2-8-25-21/h2,5-8,11-13H,1,3-4,9-10H2,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9073876 (2015) BindingDB Entry DOI: 10.7270/Q28S4NPC
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