Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Arachidonate 5-lipoxygenase-activating protein' and Ligand = 'BDBM168843'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM168843 (US9079866, 242 | US9745328, Compound 242 | US98848...) Show SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1ccccc1Sc1ccnc(N)n1 Show InChI InChI=1S/C20H15FN6S/c21-15-9-12(5-6-14(15)16-10-26-18(22)11-25-16)13-3-1-2-4-17(13)28-19-7-8-24-20(23)27-19/h1-11H,(H2,22,26)(H2,23,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9884878 (2018) BindingDB Entry DOI: 10.7270/Q2R78H8P
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM168843 (US9079866, 242 | US9745328, Compound 242 | US98848...) Show SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1ccccc1Sc1ccnc(N)n1 Show InChI InChI=1S/C20H15FN6S/c21-15-9-12(5-6-14(15)16-10-26-18(22)11-25-16)13-3-1-2-4-17(13)28-19-7-8-24-20(23)27-19/h1-11H,(H2,22,26)(H2,23,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9079866 (2015) BindingDB Entry DOI: 10.7270/Q2FF3R3Q
					More data for this Ligand-Target Pair