Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Arachidonate 5-lipoxygenase-activating protein' and Ligand = 'BDBM50080247'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM50080247 (3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(2-m...) Show SMILES Cc1nc(COc2ccc3n(Cc4ccc(Cl)cc4)c(CC(C)(C)C(O)=O)c(SC(C)(C)C)c3c2)cs1 Show InChI InChI=1S/C29H33ClN2O3S2/c1-18-31-21(17-36-18)16-35-22-11-12-24-23(13-22)26(37-28(2,3)4)25(14-29(5,6)27(33)34)32(24)15-19-7-9-20(30)10-8-19/h7-13,17H,14-16H2,1-6H3,(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description Measuring the affinity of leukotriene synthesis inhibitor for 5-lipoxygenase activating protein by using [125I]-L-691,831 as radioligand.				Bioorg Med Chem Lett 9: 2391-6 (1999) BindingDB Entry DOI: 10.7270/Q26T0KTJ
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