Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Atrial natriuretic peptide receptor 1 (Rattus norvegicus) | BDBM50230984 (CHEMBL4099832) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 23 | n/a | n/a | n/a | n/a |
Asubio Pharma Co., Ltd Curated by ChEMBL | Assay Description Agonist activity at rat NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 15 mins by fluorescent assay | Bioorg Med Chem 25: 1762-1769 (2017) Article DOI: 10.1016/j.bmc.2017.01.026 BindingDB Entry DOI: 10.7270/Q2VX0JR5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Atrial natriuretic peptide receptor 1 (Homo sapiens (Human)) | BDBM50230984 (CHEMBL4099832) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Asubio Pharma Co., Ltd Curated by ChEMBL | Assay Description Agonist activity at human NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 30 mins by radioimmunoassay | Bioorg Med Chem 25: 1762-1769 (2017) Article DOI: 10.1016/j.bmc.2017.01.026 BindingDB Entry DOI: 10.7270/Q2VX0JR5 | |||||||||||
More data for this Ligand-Target Pair |