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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Atrial natriuretic peptide receptor 1' and Ligand = 'BDBM50262434'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Atrial natriuretic peptide receptor 1


(Homo sapiens (Human))		BDBM50262434
PNG
(CHEMBL4086415)
Show SMILES CC(C)Nc1nc(NCc2ccccc2NC(=O)C2CCCN(C)C2)c2cc(ccc2n1)-c1ccccc1
Show InChI InChI=1S/C31H36N6O/c1-21(2)33-31-35-28-16-15-23(22-10-5-4-6-11-22)18-26(28)29(36-31)32-19-24-12-7-8-14-27(24)34-30(38)25-13-9-17-37(3)20-25/h4-8,10-12,14-16,18,21,25H,9,13,17,19-20H2,1-3H3,(H,34,38)(H2,32,33,35,36)
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PC cid
PC sid
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Similars
Article
PubMed
n/an/an/an/a 1.40E+3n/an/an/an/a



Asubio Pharma Co. Ltd, 6-4-3, Minatojima-Minamimachi, Chuo-ku, Kobe 650-0047, Japan. Electronic address: iwaki.takehiko.v7@asubio.co.jp.

Curated by ChEMBL


Assay Description
Agonist activity at human NPR-A expressed in CHO cells assessed as increase in intracellular cGMP accumulation after 30 mins in presence of 1-methyl-...

Bioorg Med Chem Lett 27: 4904-4907 (2017)


Article DOI: 10.1016/j.bmcl.2017.09.028
BindingDB Entry DOI: 10.7270/Q279475J
More data for this
Ligand-Target Pair