Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Atrial natriuretic peptide receptor 1 (Homo sapiens (Human)) | BDBM50262485 (CHEMBL4098800) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 310 | n/a | n/a | n/a | n/a |
Asubio Pharma Co. Ltd, 6-4-3, Minatojima-Minamimachi, Chuo-ku, Kobe 650-0047, Japan. Electronic address: iwaki.takehiko.v7@asubio.co.jp. Curated by ChEMBL | Assay Description Agonist activity at human NPR-A expressed in CHO cells assessed as increase in intracellular cGMP accumulation after 30 mins in presence of 1-methyl-... | Bioorg Med Chem Lett 27: 4904-4907 (2017) Article DOI: 10.1016/j.bmcl.2017.09.028 BindingDB Entry DOI: 10.7270/Q279475J | |||||||||||
More data for this Ligand-Target Pair |